Extrahepatic manifestations of hepatitis C

Dermatologic Extrahepatic Manifestations of Hepatitis C

Hepatitis C virus (HCV) affects millions of people worldwide, and an estimated 3.2 million people in the United States. HCV is a hepatotropic and lymphotropic virus that causes not only liver disease, but also a significant number of extrahepatic manifestations (EHMs). Up to 74% of patients affected by HCV will have HCV-related EHMs of some severity in their lifetime. The EHMs vary from simple ...

Extrahepatic manifestations in hepatitis C virus infection

Hepatitis C virus predominantly affects the liver, although it may also produce a number of extrahepatic manifestations, such as mixed cryoglobulinemia, salivary and lacrimal gland dysfunction, and several types of kidney disease. The pathogenesis of these conditions is not completely understood, but immunologic mechanisms are involved in many cases. In some patients with hepatitis C virus infe...

Extrahepatic manifestations of viral hepatitis

Morphologic Features of Extrahepatic Manifestations of Hepatitis C Virus Infection

Cirrhosis and hepatocellular carcinoma are the prototypic complications of chronic hepatitis C virus infection in the liver. However, hepatitis C virus also affects a variety of other organs that may lead to significant morbidity and mortality. Extrahepatic manifestations of hepatitis C infection include a multitude of disease processes affecting the small vessels, skin, kidneys, salivary gland...

Extrahepatic autoimmune manifestations of chronic hepatitis C virus infection.

The hepatitis C virus infection (HCV) is currently a worldwide health problem. The chronic infection may progress to cirrhosis with the subsequent development of complications including ascities, encephalopathy, upper gastrointestinal tract bleeding and hepatocellular carcinoma. The HCV is a linear, single-stranded RNA virus of the Flaviviridae family that was identified in 1989 by Choo et al. ...